DermAtlas: Online Dermatology Image Library dermatology image,toxic epidermal necrolysis,Stevens-Johnson syndrome,pearly penile papules,condyloma acuminatum,wart, anogenital,gynecomastia,Klinefelter syndrome,scabies,Crohn disease,inflammatory bowel disease

© 2001-2010, DermAtlas	*Image Name:*	TEN_10_100716	*File Type:*	jpg
	*Diagnosis:*	TOXIC EPIDERMAL NECROLYSIS / STEVENS-JOHNSON SYNDROME	*Category:*	vesiculobullous eruptions / hypersensitivity
	*Body Site:*	total body / leg groin / penis scrotum / urethra	*Age:*	5 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	Generalized erythema, blistering, and erosions
	*Comments:*	This 5-year-old boy, who was on no medications, developed fever and sore throat followed 3 days later by an erosive conjunctivitis, oral mucositis, urethritis, and a progressive generalized erythema, blistering, and ulcerations. He was admitted to the intensive care unit where he received pulsed high dose intravenous steroids and intravenous immunoglobulin 2 grams/kg over 3 days, but continued to progress to 100% skin and mucous membrane involvement. Over the subsequent 4 weeks he gradually improved and was discharged from the acute care hospital to a longterm pediatric facility for occupational and physical therapy.
	*Related Images:*	All related Images TEN_9_100716 TEN_8_100716 TEN_7_100716 TEN_6_100716 TEN_5_100716 TEN_4_100716 TEN_3_100716 TEN_2_100716 TEN_1_100716

© 2001-2010, DermAtlas	*Image Name:*	Pearly_penile_papules_1_100606	*File Type:*	jpg
	*Diagnosis:*	PEARLY PENILE PAPULES	*Category:*	normal physiologic variant
	*Body Site:*	penis / glans penis	*Age:*	23 years
	*Contributor:*	Bogdan Sgondescu
	*Description:*	uniform 1-2 mm pearly hypopigmented papules I would like to know if i have HPV or not, you can find more pictures at http://www.mypicx.com/10282009/info/ There if you click on the pictures you can zoom Thank you for your help
	*Comments:*	These papules undoubtedly represent a normal physiologic variant and do not require further evaluation or treatment. The asymptomatic lesions were present for over a year.

© 2001-2010, DermAtlas	*Image Name:*	Genital_warts_1_20100606	*File Type:*	jpg
	*Diagnosis:*	CONDYLOMA ACUMINATUM / WART, ANOGENITAL / WART	*Category:*	sexually transmitted disease / neoplasm, benign
	*Body Site:*	penis / scrotum	*Age:*	32 years
	*Contributor:*	Lahiri Koushik
	*Description:*	discrete and confluent warty papules
	*Comments:*	This 32-year-old man developed warty papules on the shaft of the penis and penoscrotal junction over the last 6 months.

© 2001-2010, DermAtlas	*Image Name:*	klinefelter_syndrome_2_100213	*File Type:*	jpg
	*Diagnosis:*	GYNECOMASTIA / KLINEFELTER SYNDROME	*Category:*	genodermatosis/genetic disorder / endocrine disorder / dysmorphology
	*Body Site:*	genital / penis testicle / scrotum	*Age:*	47 years
	*Contributor:*	Amr Gohar, MRCPS Glasgow
	*Description:*	small testicles (4 ml measured by orchidometer)
	*Comments:*	A 47-year old man who was recently married for the third time was evaluated for erectile dysfunction which had been marked over the past few years and failed to respond to oral phosphodiesterase-5 inhibitors (PDE5i). He failed to impregnate his previous two wives. On examination, the tall (190 cm) patient�s testicles were found to be small and firm (4 ml measured by orchidometer). Bilateral gynaecomastia was evident. He had fructose positive azoospermia though the seminal fructose was found to be low (8.1 �mol/ejaculate). Gonadotropins were markedly elevated. Total and free testosterone were very low. Karyotype testing showed 47, XXY. Diagnosis of Klinefelter�s syndrome was made. Testosterone replacement therapy did not significantly improve his erectile dysfunction which was successfully treated with combined testosterone replacement therapy and oral sildenafil. It should be noted that a threshold serum testosterone level is required to achieve full efficacy with PDE5i. Klinefelter�s syndrome was named after Harry Klinefelter, an endocrinologist at Massachusetts General Hospital, in 1942 who thought it was an endocrine disorder due to lack of a second testicular hormone that he postulated but was unable to identify. The postulated hormone, inhibin, was isolated later. The 47, XXY karyotype characteristic of Klinefelter syndrome was first described in Scotland in 1959.
	*Related Images:*	All related Images klinefelter_syndrome_3_100213 klinefelter_syndrome_1_100213

© 2001-2010, DermAtlas	*Image Name:*	Pearly_penile_papules_1_091120	*File Type:*	jpg
	*Diagnosis:*	PEARLY PENILE PAPULES	*Category:*	lumps & bumps (plaques, nodules, tumors) / normal physiologic variant
	*Body Site:*	penis / glans penis	*Age:*	22 years
	*Contributor:*	Popescu Fane
	*Description:*	pearly 1-2 mm smooth topped papules
	*Comments:*	These innocent asymptomatic papules were noted at the base of the glans penis of this healthy young adult.

© 2001-2010, DermAtlas	*Image Name:*	scabies_2_090731	*File Type:*	jpg
	*Diagnosis:*	SCABIES	*Category:*	infections and infestations / papulosquamous eruptions
	*Body Site:*	abdomen / thigh penis / hip	*Age:*	32 years
	*Contributor:*	Clemens Esche, MD
	*Description:*	symmetric excoriated 1-3 mm elongated papules with overlying scale
	*Comments:*	This 32-year-old man developed itchy papules on the palms, wrists, arms, legs, abdomen, and genital area. Note the typical burrows on the wrists.
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© 2001-2010, DermAtlas	*Image Name:*	crohn_disease_1_090905	*File Type:*	jpg
	*Diagnosis:*	CROHN DISEASE / INFLAMMATORY BOWEL DISEASE	*Category:*	granulomatous disorder / gastrointestinal disorder / cutaneous sign of systemic disease
	*Body Site:*	genital / scrotum penis / perineum diaper area / groin	*Age:*	5 years
	*Contributor:*	Adrianna Jackson
	*Description:*	firm rubbern non-pitting edema with surrounding red papules and pustules
	*Comments:*	This 5-year-old boy had a history of progressive swelling of the scrotum and penis for 6 months. He was growing and developing normally. Although the involved area was only moderately tender, he was extremely uncomfortable as the swelling increased and had difficulty walking. He also had chronic constipation with overflow diarrhea intermittently.
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© 2001-2010, DermAtlas	*Image Name:*	crohn_disease_2_090905	*File Type:*	jpg
	*Diagnosis:*	CROHN DISEASE / INFLAMMATORY BOWEL DISEASE	*Category:*	granulomatous disorder / gastrointestinal disorder / cutaneous sign of systemic disease
	*Body Site:*	genital / scrotum penis / perineum diaper area / groin	*Age:*	5 years
	*Contributor:*	Adrianna Jackson
	*Description:*	firm rubbern non-pitting edema with surrounding red papules and pustules
	*Comments:*	This 5-year-old boy had a history of progressive swelling of the scrotum and penis for 6 months. He was growing and developing normally. Although the involved area was only moderately tender, he was extremely uncomfortable as the swelling increased and had difficulty walking. He also had chronic constipation with overflow diarrhea intermittently.
	*Related Images:*	All related Images crohn_disease_6_090905 crohn_disease_5_090905 crohn_disease_4_090905 crohn_disease_3_090905 crohn_disease_1_090905

© 2001-2010, DermAtlas	*Image Name:*	crohn_disease_3_090905	*File Type:*	jpg
	*Diagnosis:*	CROHN DISEASE / INFLAMMATORY BOWEL DISEASE	*Category:*	granulomatous disorder / gastrointestinal disorder / cutaneous sign of systemic disease
	*Body Site:*	genital / scrotum penis / perineum diaper area / groin	*Age:*	5 years
	*Contributor:*	Adrianna Jackson
	*Description:*	firm rubbern non-pitting edema with surrounding red papules and pustules
	*Comments:*	This 5-year-old boy had a history of progressive swelling of the scrotum and penis for 6 months. He was growing and developing normally. Although the involved area was only moderately tender, he was extremely uncomfortable as the swelling increased and had difficulty walking. He also had chronic constipation with overflow diarrhea intermittently.
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© 2001-2010, DermAtlas	*Image Name:*	crohn_disease_4_090905	*File Type:*	jpg
	*Diagnosis:*	CROHN DISEASE / INFLAMMATORY BOWEL DISEASE	*Category:*	granulomatous disorder / gastrointestinal disorder / cutaneous sign of systemic disease
	*Body Site:*	genital / scrotum penis / perineum diaper area / groin	*Age:*	5 years
	*Contributor:*	Jakki Junkins-Hopkins
	*Description:*	fThe specimen shows loose aggregates o fepithelioid histiocytes and multinucleated giant cells within the dermis and subcutaneous tissue. These are also noted amidst the skeletal muscle bundles towards the base of of the biopsy. There is an associated lymphocytic infiltrate within the dermis and epidermis. The epidermis shows exocytosis of lymphocytes and spongiosis.
	*Comments:*	The clinical-pathologic featuers favor cutaneous Crohns disease. Stains for fungi, acid fast bacilli, and spirochetes were negative.
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